AARP Hearing Center

I take ibuprofen (Advil) nearly every day for muscle aches, headaches and pain. Is that a problem?
Like you, a lot of people rely on NSAIDs (nonsteroidal anti-inflammatory drugs) such as ibuprofen, naproxen or aspirin to relieve their pain, lower fever or reduce inflammation. You may recognize the brand names of these drugs as Advil, Motrin, Aleve and Bayer.
Several of my patients have told me, “Dr. Adam, these pills are the best. I won’t start my day without taking them.”
But that can be a problem. There’s a perception that just because medications are sold over the counter, they’re always safe. This is simply not the case. Even though these drugs are effective, they can have serious side effects, particularly if you don’t follow the dosing limitations.
For instance, ibuprofen can be hard on your tummy. If you’ve been taking this drug for longer than a few weeks or are taking more than the recommended daily amount, you’re leaving yourself open to gastrointestinal problems.
Even a single dose of non-steroidal therapy can cause gastritis, which is an inflammation or irritation of the stomach lining. You might experience heartburn or acid reflux. In extreme cases, NSAIDs can lead to bleeding in your stomach or esophageal ulcers; either can be life-threatening.

Ask Dr. Adam
Adam B. Rosenbluth, M.D., is an internist and cardiologist in New York City. Each Monday, he’ll weigh in on your questions about how to make your body work better for you. His AARP book will be published in 2027. Join in on the conversation on social media @dradamrosenbluth to learn to move the needle on your personal health in an achievable way.
To help protect the tummy, I tell my patients they should always eat something before taking ibuprofen. If you know that you’re prone to acid reflux or indigestion, you might want to pre-empt problems by combining the non-steroidal with an over-the-counter antacid medication.
Ibuprofen can also cause kidney problems, especially if you become dehydrated. I know this firsthand. My mother was hospitalized because she wasn’t drinking enough water while she was taking a lot of Advil for arthritis pain. NSAIDs can increase your risk of dehydration because they may make it harder for your kidneys to maintain fluid balance, and you may sweat more when you’re taking the drug.
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