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Key takeaways
- Mosquitoes, ticks and fleas can be infected with viruses, bacteria and the like and transmit them to humans.
- Some illnesses that you can get from insects cause long-lasting complications, while others can be severe, especially for older adults.
- Knowing which insects are a problem in your area and taking steps to prevent bites is important.
Some bugbites are more than just itchy — they can make you seriously sick. And in warmer months, your risk of getting an insect-borne illness from mosquitoes, ticks, fleas and other bugs rises.
While trends can ebb and flow, there’s “absolutely” an uptick in insect-borne diseases, says Dr. Beth Kirkpatrick, an infectious disease doctor at the University of Vermont Medical Center. According to the Centers for Disease Control and Prevention (CDC), cases more than doubled between 2001 and 2023.
Also growing: the threat of getting bitten by an insect carrying multiple, different disease-causing germs. An Ecosphere study that came out in 2025 showed that approximately 1 in 10 juvenile deer ticks in the Northeast U.S. carry two or more different disease-causing pathogens.
Why bugbites — and diseases from them — are rising
Climate change has helped fuel the rise in insect-borne diseases. Milder winters, for example, allow more ticks to survive the colder months than have in the past. But climate isn’t the only factor: A lot of it has to do with other ways that humans have modified the environment, says Jonathan Oliver, an associate professor in environmental health sciences at the University of Minnesota School of Public Health.
Changing land-use patterns have led to booming mice, deer and chipmunk populations in suburban areas, the CDC explains, and these animals harbor ticks. What’s more, global travel can introduce insect-borne illnesses not often seen in the U.S., such as chikungunya and Zika.
8 diseases you can get from a bugbite
Here are eight of the more common diseases transmitted by insects.
1. Lyme disease
Lyme disease is the most common insect-borne disease in the U.S. You can get it if you’re bitten by a deer tick (also known as a black-legged tick) that’s infected with the bacteria Borrelia burgdorferi.
In the past 30 years or so, the geographic range of deer ticks has expanded. They used to only be found in the northern parts of the U.S., but they now exist in the Midwest, Oliver says. The proportion of infected ticks has also grown, he notes. In April, emergency room visits for tick bites were up more than 25 percent from a year ago, according to the CDC. In 2023 there were more than 89,000 cases of Lyme disease in the U.S. Other estimates say that about 476,000 people are diagnosed and treated for Lyme disease each year in this country.
Where is it? You can encounter Lyme disease throughout the U.S., but it’s more commonly found along the Eastern Seaboard and in the Great Lakes region.
Symptoms: Sometimes you’ll see a bull’s-eye rash at the site of the bite in three to 30 days. Other early symptoms of Lyme disease include headache, fatigue, swollen lymph nodes, stiff joints, muscle aches and fever.
Diagnosis: Lyme disease is diagnosed with a blood test.
Treatment: Most cases of Lyme disease can be treated with antibiotics, and people who take antibiotics early in the disease course typically recover quickly and completely, the CDC says. Some people will experience lingering symptoms like fatigue or pain — something called post-treatment Lyme disease syndrome.
Currently there is no vaccine to prevent Lyme disease. However, that could change. In March, Pfizer and specialty vaccine company Valneva announced that its phase 3 trial for a Lyme disease vaccine showed about 70 percent efficacy. It requires multiple doses but could be a good option for those at high risk for the disease, Kirkpatrick says.
2. West Nile virus
West Nile virus is the most common mosquito-borne disease in the U.S., with diagnoses peaking in late August and September. Infected culex species mosquitoes can pass it on to humans. Humans, however, don’t develop high levels of the virus and, therefore, can’t pass it on to other mosquitoes.
In 2025 there were 2,076 cases of West Nile virus in the U.S. One in 5 people get sick when an infected mosquito bites them, but those over the age of 65 tend to get more severely sick from the disease and are three times more likely to have a neurological illness compared with younger demographics, the CDC reports.
Where is it? West Nile virus has been found nationwide, with the exception of Hawai‘i and Alaska.
Symptoms: The virus can cause flu-like symptoms, which can start two to six days after a bite by an infected mosquito or up to 14 days post-bite. If you have a weakened immune system, it may take longer for symptoms to develop. About 80 percent of infected people don’t have symptoms, the CDC reports.
Diagnosis: West Nile virus is diagnosed with a blood test or a cerebrospinal fluid (spinal tap) test.
Treatment: There are no specific medicines available to treat West Nile virus; the CDC says rest, fluids and pain medications may relieve some symptoms. Fewer than 1 percent of people develop severe illness that could impact their central nervous system, require hospitalization or cause death.
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