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Welcome to Ethels Tell All, where the writers behind The Ethel newsletter share their personal stories related to the joys and challenges of aging. Come back Wednesday each week for the latest piece, exclusively on AARP Members Edition.
A few decades ago, I participated in a “swab-a-thon” to sign new people up for the U.S. bone marrow donor registry. It involved completing a few forms and rubbing a cotton swab in my mouth for a few minutes.
As fate would have it, on that same day in 2023, my husband, Ethan, and I were told by his doctor that the chemo-only approach they’d tried to cure his acute lymphoblastic leukemia (ALL) wasn’t working. His only chance of survival was a bone marrow transplant. “But don’t worry,” the doctor told us, “we’ve already found five potential matches for you on the registry.”
I couldn’t help but think that karma was doing us a solid.
Bone marrow transplants have been around since the late 1950s. According to The Cleveland Clinic, they help treat blood cancers and disorders like leukemia, lymphoma and sickle cell disease. In those early procedures, doctors would drill into donors’ hip bones to extract bone marrow, which was then transfused into recipients.
Thanks to scientific advancements, 90 percent of all donations now use peripheral blood stem cells, which can be collected non-surgically in a process similar to donating plasma or platelets, according to the NMDP (formerly Be the Match), which administers the national marrow donor program in the United States.
Recipients and donors have to be genetic matches. That’s why there’s a need for a donor registry — not just in the U.S., but across the world. As an only child, Ethan’s closest familial genetic matches were his dad and our sons, which were naturally only a 50 percent match (known as haploidentical) at best. Transplants with haploidentical donors are possible, but doctors strive to find a match as close to perfect as they can.
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