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This is a well-traveled, unforgettable American road trip, taking you westward through the varied landscape and historic sites of South Dakota. It includes the otherworldly sandstone cliffs and towers of the Badlands, iconic destinations like Wall Drug, Mount Rushmore National Monument, Crazy Horse Monument and Custer State Park, and finally, the storied outlaw town of Deadwood. The itinerary described below kicks off in Minneapolis (about four hours from Sioux Falls). Depending on where you live, you could instead start your trip from Des Moines (also about a four-hour drive) or Kansas City (a little over five hours) without missing the route's biggest highlights. And note that if you have the time and inclination to extend your four-day road trip, from Deadwood you're only about six or seven hours from two incredible national parks: Yellowstone to the west and Rocky Mountain to the south.
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COVID-19 Update
The unpredictability of the coronavirus means travel restrictions are constantly evolving. Be sure to check the Minnesota and South Dakota official websites for updates, and follow Centers for Disease Control and Prevention guidelines for safe travel.
Day 1: Minneapolis to Sioux Falls (240 miles)
The southwestern route out of Minneapolis along U.S. 169 follows the lush Minnesota River Valley through a string of historic river towns including Jordan, about 40 miles away, which has 15 buildings on the National Register of Historic Places and the state's largest candy store at Jim's Apple Farm. Minneapolis-born Prince made his 1984 movie Purple Rain along this stretch of river. Stop in Henderson, about 20 miles on, to pay homage to the musician at the new statue erected in his honor. Drive another 30 miles to find Mankato, and take a picnic (or sandwiches from downtown's Wooden Spoon) to Minneopa Falls, which tumbles over limestone ledges, and spot a herd of reintroduced bison in Minneopa State Park.
It's about 160 miles of lakes and cornfields on Interstate 90 to Sioux Falls, where you will find panini and homemade ice cream at the Falls Overlook Café in a former 1908 hydroelectric power plant overlooking namesake Sioux Falls, of course.
Where to stay: Overnight in Sioux Falls at the Hotel on Phillips, in a repurposed 1918 bank that once was the state's tallest building at nine stories. Enjoy a craft cocktail in its lounge, in the decommissioned vault.
Day 2: Sioux Falls to Wall (290 miles)
Grab a latte at Coffea Roasterie downtown and stroll past some of the nearby 62 artworks installed as SculptureWalk. Then, hit the interstate for 75 miles to Mitchell, home to the landmark Corn Palace. Murals made of colored corn, grains and grasses decorate the Moorish structure, a monument to South Dakota's agricultural fitness dating back to 1892 (skip the indoor arena; the exterior is the main attraction).