Breast cancer staging: What the numbers mean

 | April 12, 2007

Breast cancer staging: What the numbers mean

To determine your stage, find T, N, and M classifications from your pathology report on this list. For example, the pathology report might describe a tumor that is T1, N0, M0. That means the tumor is Stage 1.

Stage groupings

Stage 0

Stage I

Stage IIA

Stage IIB

Stage IIIA

Stage IIIB

Stage IIIC

Stage IV

T (Tumor)

Tis

T1*

T0
T1*
T2

T2
T3

T0
T1*
T2
T3
T3

T4
T4
T4

Any T

Any T

N (Nodes)

N0

N0

N1 N1 N0

N1 N0

N2 N2 N2 N1 N2

N0 N1 N2

N3

Any N

M (Metastasis)

M0

M0

M0 M0 M0

M0 M0

M0 M0 M0 M0 M0

M0 M0 M0

M0

M1

*T1 includes T1mic

Interpreting the T, N, M classifications

T = Tumor

T0: No evidence of primary tumor

Tis: Carcinoma in situ

Tis (DCIS): Ductal carcinoma in situ

Tis (LCIS): Lobular carcinoma in situ

Tis (Paget's): Paget's disease of the nipple with no tumor

T1: Tumor 2 cm or less in greatest dimension

T1mic: Microinvasion 0.1 cm or less (microinvasion is a small tumor within the breast only)

T1a: Tumor more than 0.1 cm but not more than 0.5 cm in greatest dimension

T1b: Tumor more than 0.5 cm but not more than 1 cm in greatest dimension

T1c: Tumor more than 1 cm but not more than 2 cm in greatest dimension

T2: Tumor more than 2 cm but not more than 5 cm in greatest dimension

T3: Tumor more than 5 cm in greatest dimension

T4: Tumor of any size with direct extension to chest wall, skin, or both

T4a: Extension to chest wall, not including pectoralis muscle

T4b: Edema or ulceration of the skin of the breast, or scattered skin nodules confined to the same breast

N = Nodes

N0: No regional lymph node metastasis

N1: Metastasis in 1–3 lymph nodes

N2: Metastasis to 4–9 axillary (underarm) lymph nodes, or to internal mammary nodes that are clinically apparent in the absence of axillary lymph node metastasis

N3: Metastasis to 10 or more axillary lymph nodes, or

in infraclavicular lymph nodes (under the collarbone)

in clinically apparent internal mammary nodes (behind the breastbone) with 1–3 positive axillary nodes

in supraclavicular lymph nodes (above the collarbone) on the same side as the breast cancer

M = Metastasis

M0: No distant metastasis M1: Distant metastasis present MX: Distant metastasis cannot be assessed

Source: American Joint Committee on Cancer, 2002

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Review Date: 2007-04-12

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