Following established seasonal patterns, cases and hospitalizations for COVID-19, flu, and RSV were much higher in Q1 than in Q2 across the US. In the first quarter of 2025, there were 96 confirmed cases of respiratory illnesses (COVID-19, flu, and RSV) and 13 hospitalizations per 1000 residents for these illnesses. COVID-19 was the most prevalent of these illnesses, while influenza was the most common cause of hospitalization. This corresponds to about 120,000 total cases and 16,000 total hospitalizations in the quarter. In the second quarter, the rate of cases declined by 80% and the rate of hospitalizations dropped by 85% to approximately 20 cases and 2 hospitalizations per 1000 residents (approximately 24,000 total cases and 2,000 total hospitalizations), the majority of which were due to COVID-19.