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When it comes to dietary supplements, what’s on the label isn’t always what’s inside the bottle. New research shows that’s the case with galantamine, a plant extract that’s marketed by some companies as a memory booster.
In the U.S., galantamine is also sold as a prescription medication for the treatment of Alzheimer’s disease symptoms. It’s not the only medication you can find as both a supplement and a prescription drug; others include potassium, niacin and vitamin D.
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In a new study, published Feb. 23 in the journal JAMA, researchers investigated the label accuracy of prescription galantamine, sold as a generic, and galantamine sold as a supplement. When examining 10 different brands of galantamine supplements — labeled as containing 4, 6, 8 or 12 mg of galantamine per serving — the researchers found that the actual quantity of galantamine ranged from less than 2 percent to 110 percent of the labeled quantity.
The quantity of galantamine in the prescription bottles, labeled as containing 4, 8 or 12 mg of galantamine per pill, was much closer to what was printed on the bottle, ranging from 97.5 percent to 104.2 percent of the labeled content.
The findings have a few implications, especially for older adults, says internist Pieter Cohen, M.D., the lead author on the study and an associate professor of medicine at Harvard Medical School.
“If anyone [diagnosed with Alzheimer’s disease] thinks it’s going to be a bargain to buy their galantamine over the counter rather than getting a prescription version, it’s not going to work out well at all, because they’re not going to get an accurate amount of galantamine,” he says. “If your doctor prescribes galantamine, make sure you’re getting a prescription version of it.”
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