Skip to content

NIH-AARP Diet and Health Study: Impact of Diet and Lifestyle Factors on Cancer Incidence: Weight Change

Energy Balance | Weight Change

For a copy of these publications and others related to the NIH-AARP Diet and Health Study, visit the National Cancer Institute.

Lifetime Weight History and Endometrial Cancer Risk by Type of Menopausal Hormone Use in the NIH-AARP Diet and Health Study
Current adiposity and adult weight gain in women are associated with substantial increases in the risk of endometrial cancer. The association is particularly evident among never users of menopausal hormone therapy, according to findings from the National Institutes of Health-AARP Diet and Health Study. In a five-year following up of 103,882 women ages 50-71, 677 cases of endometrial cancer developed.

  • High body mass index (BMI) at baseline and adult weight gain were associated with increased endometrial cancer risk
  • Consistent overweight or obesity during adult hood was associated with greater risk of endometrial cancer than being overweight or obese only in later adult life
  • Menopausal hormone therapy was independently associated with increased risk of endometrial cancer.
  • The relationship between both BMI and adult weight gain and endometrial cancer risk were stronger among nonusers than among current or former users of menopausal hormones.

Prospective Study of Adiposity and Weight Change in Relation to Prostate Cancer Incidence and Mortality

Does being obese or even overweight increase a man's risk of developing prostate cancer and dying from it? No to developing the disease, yes to dying once it develops.

Further information about the study or individual reports may be obtained by contacting Nancy Wood of AARP at or 202-434-2583.

« back to list of NIH-AARP Diet and Health Study reports

Join the Discussion

0 | Add Yours

Please leave your comment below.

You must be logged in to leave a comment.