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NIH-AARP Diet and Health Study: Impact of Diet and Lifestyle Factors on Cancer Incidence: Esophageal and Gastric Cancer

Cancer Sites | Esophageal & Gastric

For a copy of these publications and others related to the NIH-AARP Diet and Health Study, visit the National Cancer Institute.

A Prospective Study of Tobacco, Alcohol, and the Risk of Esophageal and Gastric Cancer Subtypes
Tobacco and alcohol use are associated with increased risk for some types of esophageal and gastric cancers, according to data gathered by the National Institutes of Health-AARP Diet and Health Study on 474,606 U.S. participants. Between 1995/1996 and 2000, 97 participants were diagnosed with esophageal squamous cell carcinoma (ESCC), 205 with esophageal adenocarcinoma, 188 with gastric cardia adenocarcinoma, and 187 with gastric noncardia adenocarcinoma.

  • Compared with nonsmokers, current smokers were at increased risk for all 4 cancer subtypes. The proportion of these cancers in participants due to smoking was 77% for ESCC, 58% for esophageal adenocarcinoma, 47% for gastric cardia, and 19% for gastric noncardia.
  • Those who consumed more than 3 alcoholic beverages per day, compared with those whose intake was up to 1 drink per day, increased their risk for ESCC but not the other 3 cancer subtypes.

Further information about the study or individual reports may be obtained by contacting Nancy Wood of AARP at or 202-434-2583.

« back to list of NIH-AARP Diet and Health Study reports

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