Four Seasons (Borgo Pinti 99; www.fourseasons.com/florence; tel. 055-2626-250)
There was never really any doubt, when the Palazzo della Gherardesca reopened in 2009 as the Four Seasons Firenze after a 7-year restoration project -- this was destined to be the most luxurious address in Tuscany. Original frescoes on the 15th-century walls, sumptuous decor, and some of the city's finest dining are just a few of the earthly delights you'll find here.
Helvetia & Bristol (Via dei Pescioni 2; www.royaldemeure.com; tel. 055-26-651)
This most central of Florence's luxury addresses was the city's leading hotel in the 19th century, and guest rooms and lounges still exude an opulent turn-of-the-20th-century air. The bright and refreshing small Winter Garden bar, with trailing ivy and a splashing fountain, doubles as the breakfast room. The location, opposite the Strozzi and a few paces from Via de' Tornabuoni, could hardly be better for a shopping- and culture-fueled visit.
Residence Hilda (Via dei Servi 40; www.residencehilda.it; tel. 055-288-021)
Step off the Renaissance square of Santissima Annunziata right into the 21st century at this apartment building, where clean, contemporary design is complemented by high-quality modern conveniences. Add hotel amenities to those cool, airy spaces, stripped-wood floors, and cream walls and fabrics, then throw in a management team who can't do enough to help you out, and you have just about the perfect Florence accommodation package. Oh, and did we mention it's just 2 blocks from the Duomo?
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Note: This information was accurate when it was published, but can change without notice. Please be sure to confirm all rates and details directly with the companies in question before planning your trip.