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Add Creatine to the list of supplements that increase glucose disposal rates in muscles. There is so much scientific evidence for this that I am angry that my MDs didn't tell me about this. Creatine Monohydrate is so inexpensive that any T2 diabetic who shows signs of insulin resistance in muscles, after being alerted to this, would be a damn fool to not try it. It can be purchased for $14.75/kg at
Yesterday, I started taking about 10 g of creatine monohydrate with meals. Otherwise, I followed a routine that I had followed many times before. I take 500 mg metformin 4 times a day and 10 mg glipizide twice a day with meals. Also, I take alpha lipoic acid and acetyl L-carnitine. My last meal was at 7:30 pm and it was one that typically caused my blood glucose reading to be about 140 mg/dl at 11:30 pm and 120 mg/dl at 8:30 am the next morning. But, this time, after taking creatine, I developed symptoms of hypoglycemia at 10:25 pm, and my blood glucose was 68 mg/dl. Then I pigged out too much on glucose based candy, specifically, Wonka Bottle Caps. At 11:30 pm, my blood glucose was 181 mg/dl. Normally, under such circumstance, I would take another glipizide pill before going to bed. But, this time, instead, I took another 5 g of creatine monohydrate. After sleeping, this morning, my blood glucose was 99 mg/dl at 8:30 am.
I should mention that the above was after I walked 10 miles for exercise. I exercise three times a week and my glucose readings on exercise days are almost the same as readings on days on which I do not exercise. I take this as evidence of insulin resistance in my muscles because, otherwise, glucose disposal should be much greater after exercise in order to replenish depleted glycogen stores in the muscles. Incidentally, my fasting free serum insulin is 4.8 uIU/ml which is normal and, as such, does not indicate insulin resistance. But, I have been slowly losing weight and growing weaker therefore I suspect that glucose has been preferentially shuttled to my fat cells and liver while my muscles are being starved for glucose. I hope creatine supplementation prevents further muscle wasting.
Anyway, yesterday was a non-exercise day and creatine had less effect on my blood glucose. It was 108 mg/dl immediately before and immediately after sleep.