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Using Medications Wisely

Milk Thistle 101

You may have heard of Milk Thistle. It is believed to protect the liver and improve its function. It is typically used to treat liver cirrhosis, chronic hepatitis (liver inflammation), and gallbladder disorders. Treatment claims also include:

  • Lowering cholesterol levels
  • Reducing insulin resistance in people with type 2 diabetes who also have cirrhosis
  • Reducing the growth of cancer cells in breast, cervical, and prostate cancers

What the Science Says
There have been some small studies of milk thistle on liver disease. While some promising data have been reported, the study results are mixed. To date, there is no conclusive evidence to prove its claimed uses.

The National Center for Complementary and Alternative Medicine (NCCAM) is supporting a research study to better understand the use of milk thistle for chronic hepatitis C. Together, NCCAM and the National Institute of Diabetes and Digestive and Kidney Diseases, are planning further studies of milk thistle for chronic hepatitis C and nonalcoholic steatohepatitis (liver disease that occurs in people who drink little or no alcohol).

The National Cancer Institute and the National Institute of Nursing Research are also studying milk thistle, for cancer prevention and to treat complications in HIV patients.

Side Effects and Cautions
In clinical trials, milk thistle generally has few side effects. Occasionally, people report a laxative effect, upset stomach, diarrhea, and bloating.

Milk thistle can produce allergic reactions, which tend to be more common among people who are allergic to plants in the same family (for example, ragweed, chrysanthemum, marigold, and daisy).

Remember: It is important to inform your health care providers about any herbal or dietary supplement you take, including milk thistle. This helps to ensure safe and coordinated care.

For more information, visit: http://nccam.nih.gov/health/milkthistle/

Source: National Center for Complementary and Alternative Medicine (NCCAM), National Institutes of Health

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