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Study Finds Aspirin May Reduce Prostate Cancer Deaths

Blood-thinning, anti-inflammatory effect could be key

Most of the nearly 2,000 men studied were taking aspirin, and some took warfarin (Coumadin), other blood thinners or a combination of medications.

"We found that prostate cancer mortality was significantly lower if you were on one of these medications," Choe said. "When we looked further at which of these medications was most important for this reduction, we found that it was aspirin that seemed to have the biggest benefit."

Christopher Logothetis, M.D., a medical oncologist at the University of Texas MD Anderson Cancer Center in Houston, said the study is in line with others that suggest aspirin's blood-thinning and anti-inflammatory properties reduce the risk of many kinds of cancer.

Such studies tend to look at existing patient records and can only determine associations, not explain why aspirin might help beat prostate cancer, he notes. He concedes there haven't been any studies where some men received aspirin and others a placebo to see what the differences might be.

But Logothetis says based on the evidence, it is "reasonable" for doctors to recommend a small daily dose of aspirin to their prostate cancer patients, except for those patients who are allergic to the medication, suffer from ulcers or have bleeding problems.

Choe was a little more cautious, saying further studies should be done before making routine recommendations to give aspirin to prostate cancer patients, but if you are already taking aspirin "then you may have additional benefit for your prostate cancer as well."

Michael Haederle is a freelance writer whose work has appeared in People, the New York Times and the Los Angeles Times.

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