The Big 5-Oh: January 13
"You can only fight age so hard," the Emmy-winning star of Seinfeld and The New Adventures of Old Christine once said. "Then you just have to stand up straight and be graceful."
Maybe her self-assured mix of edginess and goofy glamour is nurtured by her 23-year marriage to fellow Saturday Night Live alumnus Brad Hall, or maybe by their two children.
Now she's 50, and as a sitcom character once said, "Not that there's anything wrong with that."