He broke up with Cruz — and soon his heart was roaring for actress Katie Holmes. Some thought Cruise was off his rocker when he famously jumped up and down on Oprah Winfrey’s couch in 2005, declaring his love for Holmes. Alas, it was not to last forever. Holmes recently filed for divorce, after six years of marriage. They have a daughter, Suri, 6. — Lisa O'Connor/ZUMA Press/Corbis
En Español | As he turns 50 on July 3, Tom Cruise may be facing a third divorce, but remains squarely at the top of an unparalleled career. Time and again Cruise has challenged himself with ambitious new parts. His screen roles have often corresponded to personal landmarks in one of the world’s most publicly perused lives. Click through the images above to see him in his most memorable moments.