Thanks to a skull cap and a pillowy paunch, even Cruise's most ardent fans might not have recognized him as loudmouth producer Les Grossman in Ben Stiller's comedy Tropic Thunder. Actually, we thought he looked suspiciously like James Lipton, host of Inside the Actors Studio, on which Cruise guested in 2004. — DreamWorks/Photofest
En Español | As he turns 50 on July 3, Tom Cruise may be facing a third divorce, but remains squarely at the top of an unparalleled career. Time and again Cruise has challenged himself with ambitious new parts. His screen roles have often corresponded to personal landmarks in one of the world’s most publicly perused lives. Click through the images above to see him in his most memorable moments.